This web-site has been designed in an attempt to explain the biochemistry that is "behind" the development of dementia and AD, with the purpose of suggesting methods to avoid the condition and to present the possibility that it may be possible to prevent, halt or reverse the condition.
The site has been assembled following examination of a wide variety of scientific literature describing altered biochemical markers known to be present in dementia/Alzheimer's Disease, and examines the possible nutritional deficiencies that are involved, with the purpose of identifying methods to detect, prevent and hopefully reverse the disease. Where possible references have been included.
The brain/mind is a wonderful organ which performs trillions of chemical reactions that enable it to repeatedly monitor and react to the various stimuli that the body encounters, some of which may be several nanometers away and some of which may be at the periphery of the body, several meters away.
An integral part of the brain's ability to function is the preservation and maintenance of the "wiring" system (nerves), each of which is wrapped in a sheath of insulation known as the myelin sheath, and in the continued signaling or endless "neuronal firing" that allows communication between the nerves, muscles and various receptors throughout the body. In order to perform this function, the brain must be continuously supplied with energy (preferably glucose, but also ketones), vitamins and minerals, and with the essential structural building blocks (amino acids, sugars and fats).
Ageing of the brain appears to result from an interruption in supply of these nutrients either through reduced blood circulation, or due to reduced nutritional uptake into the body. In extended ageing or nutrient restriction, conditions such as dementia and Alzheimer's disease slowly develop. Accompanying this progression there is evidence of brain shrinkage. It is the purpose of this site to try to elucidate these deficiencies, to define how the supply is restricted and to propose intervention mechanisms to halt or indeed reverse this age-related decay. The views expressed are derived from an analysis of the scientific literature, they may though be slightly controversial, however for this we make no apology.
Alzheimer's Disease and Dementia
Alzheimer's disease is the most common type of dementia and poses itself as a significant worldwide health problem, with approximately 44 million people living with the condition. The diagnosis of Alzheimer's disease is life-changing not only for the person diagnosed with the condition but also for their family and friends. Currently the disease is regarded as an inevitably progressing condition in which the person with AD gradually loses activity of not only their mental, but also physical functions. Often the condition is "missed" and passed off as simply old age, as symptoms, such as memory loss, slowed thinking and moderate behavioral changes, are also generally associated with the ageing process. Once the diagnosis of the condition has been made the disease slowly progresses and variable rates of functional loss occur, which lead inevitably to death.
Currently there are no treatments to stop the disease from progressing, however many palliative medications are often prescribed, but they do not affect the inevitable outcome of the condition.
Persons wishing further information on dealing with dementia of themselves, or loved ones should consult the many regional dementia/Alzheimer's Disease institutions.
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The statements on this site compose a compendium of generally recognized signs of Alzheimer's disease. They also are formulated from a summary of relevant scientific publications. In addition they may contain some forward looking statements of a general nature.
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